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Adverse cutaneous effects of mitogen-activated protein kinase inhibitors in children

机译:丝裂原激活蛋白激酶抑制剂在儿童中的不良皮肤影响

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摘要

Background Mitogen-activated protein kinase inhibitors (MEKi) are currently used for the treatment of central nervous system tumors in children and have shown promising results. Cutaneous adverse effects are among the most common toxicities described in adults, but few studies exist in pediatric patients.
机译:背景:丝裂原活化蛋白激酶抑制剂(MEKi)目前用于治疗儿童中枢神经系统肿瘤,并已显示出良好的效果。皮肤不良反应是成人最常见的毒性反应之一,但对儿科患者的研究很少。

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