Nighttime melatonin secretion and sleep architecture: different associations in perimenopausal and postmenopausal women

摘要

Background: Sleep quality typically decreases after menopause, but the underlying mechanisms are poorly understood. Concentrations of melatonin are lower and its secretion profiles different before and after menopause. However, whether and how melatonin and sleep architecture are associated in women of different reproductive states have not been examined to date.