Changes in brain functional connectivity and cognition related to white matter lesion burden in hypertensive patients from SPRINT

Shah Chintan; Srinivasan Dhivya; Erus Guray; Schmitt James E.; Agarwal Adhish; Cho Monique E.; Lerner Alan J.; Haley William E.; Kurella Tamura Manjula; Davatzikos Christos; Bryan Robert N.; Fan Yong; Nasrallah Ilya M.

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Changes in brain functional connectivity and cognition related to white matter lesion burden in hypertensive patients from SPRINT

机译：脑功能连通性和认知与冲刺患者的白质病变负担相关的脑功能连通性和认知

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Purpose Hypertension is a risk factor for cognitive impairment; however, the mechanisms leading to cognitive changes remain unclear. In this cross-sectional study, we evaluate the impact of white matter lesion (WML) burden on brain functional connectivity (FC) and cognition in a large cohort of hypertensive patients from the Systolic Blood Pressure Intervention Trial (SPRINT) at baseline.

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《Neuroradiology》 |2021年第6期|共12页
作者
Shah Chintan; Srinivasan Dhivya; Erus Guray; Schmitt James E.; Agarwal Adhish; Cho Monique E.; Lerner Alan J.; Haley William E.; Kurella Tamura Manjula; Davatzikos Christos; Bryan Robert N.; Fan Yong; Nasrallah Ilya M.;
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作者单位

Univ Penn Dept Radiol Philadelphia PA 19104 USA;

Univ Penn Dept Radiol Philadelphia PA 19104 USA;

Univ Penn Dept Radiol Philadelphia PA 19104 USA;

Univ Penn Dept Radiol Philadelphia PA 19104 USA;

Univ Utah Div Nephrol &

Hypertens Salt Lake City UT USA;

Univ Utah Div Nephrol &

Hypertens Salt Lake City UT USA;

Case Western Reserve Univ Univ Hosp Cleveland Med Ctr Dept Neurol Cleveland OH 44106 USA;

Mayo Clin Dept Hypertens &

Nephrol Jacksonville FL 32224 USA;

Stanford Univ Div Nephrol Palo Alto CA 94304 USA;

Univ Penn Dept Radiol Philadelphia PA 19104 USA;

Univ Texas Austin Dell Med Sch Dept Diagnost Med Austin TX 78712 USA;

Univ Penn Dept Radiol Philadelphia PA 19104 USA;

Univ Penn Dept Radiol Philadelphia PA 19104 USA;

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原文格式 PDF
正文语种 eng
中图分类放射医学;
关键词
Hypertension; Functional connectivity; White matter lesions; Cognitive impairment;

机译：高血压;功能连通性;白质病变;认知障碍;
入库时间 2022-08-20 18:31:53

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1. Relationship between episodic memory and resting-state brain functional connectivity network in patients with Alzheimer’s disease and mild cognition impairment [J] . 吴钦娟中国医学文摘：内科学分册（英文版） . 2013,第003期
2. Longitudial observation of dynamic changes in cortical function and white matter fibrous structure of patients with visual pathway lesions by blood oxygenation level dependent-functional magnetic resonance imaging combined with diffusion tensor imaging [J] . 中国神经再生研究（英文版） . 2007,第008期
3. Functional regeneration of the brain：white matter matters [J] . Teng Guan, Jiming Kong 中国神经再生研究（英文版） . 2015,第003期
4. Correlation between white matter damage and gray matter lesions in multiple sclerosis patients [J] . Xue-mei Han, Hong-ji Tian, Zheng Han, 中国神经再生研究（英文版） . 2017,第005期
5. Intensive blood pressure lowering prevents mild cognitive impairment and possible dementia and slows development of white matter lesions in brain: the SPRINT Memory and Cognition IN Decreased Hypertension (SPRINT MIND) study [J] . Kjeldsen Sverre E., Narkiewicz Krzysztof, Burnier Michel, Blood pressure. . 2018,第5期

机译：压力降低血压降低了脑中白质病变的痴呆症和可能的痴呆和发动机：Sprint记忆和认知降低的高血压（冲刺态度）研究
6. Intensive blood pressure lowering prevents mild cognitive impairment and possible dementia and slows development of white matter lesions in brain: the SPRINT Memory and Cognition IN Decreased Hypertension (SPRINT MIND) study [J] . Kjeldsen Sverre E., Narkiewicz Krzysztof, Burnier Michel, Blood pressure. . 2018,第5期

机译：压力降低防止了轻度认知障碍和可能的痴呆症和脑中白质病变的发育：Sprint记忆和认知在降低的高血压（冲刺态度）研究中
7. Limitations on the developing preterm brain: Impact of periventricular white matter lesions on brain connectivity and cognition [J] . PavlovaM.A., Kr?geloh-MannI. Brain: A journal of neurology . 2013,第4期

机译：发育中的早产大脑的局限性：脑室周围白质病变对大脑连接性和认知的影响
8. FOD Restoration for Enhanced Mapping of White Matter Lesion Connectivity [C] . Wei Sun, Lilyana Amezcua, Yonggang Shi International conference on medical imaging computing and computer-assisted intervention . 2017

机译：FOD恢复以增强白色物质病变连接性的映射
9. Cognitive function and emotional status of middle-aged Chinese hypertensive patients without detectable white matter brain lesions or lacunar infarctions. [D] . Rogers, Heather L. 2006

机译：没有发现白质脑病或腔隙性脑梗塞的中年高血压患者的认知功能和情绪状态。
10. Abnormal functional connectivity density in patients with ischemic white matter lesions [O] . Ju-Rong Ding, Xin Ding, Bo Hua, -1

机译：缺血性白质病变患者的功能连接密度异常
11. Intensive blood pressure lowering prevents mild cognitive impairment and possible dementia and slows development of white matter lesions in brain: the SPRINT Memory and Cognition IN Decreased Hypertension (SPRINT MIND) study [O] . Sverre E. Kjeldsen, Krzysztof Narkiewicz, Michel Burnier, 2018

机译：压力降低血压降低了脑中白质病变的痴呆症和可能的痴呆和发动机：Sprint记忆和认知降低的高血压（冲刺态度）研究
12. Cognitive Function and Emotional Status of Middle-aged Chinese Hypertensive Patients Without Detectable White Matter Brain Lesions or Lacunar Infarctions. [R] . Rogers, H. L. 2006

机译：中年高血压患者无可检测白质脑病变或腔隙性脑梗死的认知功能和情绪状态。

Changes in brain functional connectivity and cognition related to white matter lesion burden in hypertensive patients from SPRINT

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