Carbamazepine responsive dysphagia--a variant of paroxysmal kinesigenic dyskinesia?

摘要

Paroxysmal kinesigenic dyskinesia (PKD) is characterized by brief and frequent episodes of abnormal movements triggered by sudden activities. Familial PKD is an inherited disorder, appears in teens, involves hemi-body and responds well to carbamazepine or phenytoin. Late onset cases are unusual and are secondary to a variety of insults. We present two cases of late onset, acquired, carbamazepine responsive focal PKD, where the act of swallowing induced paroxysms of abnormal laryngo-pharyngeal movements and resulted in dysphagia and chronic cough.