A case of simultaneous onset of anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis accompanied by interstitial pneumonia and pulmonary tuberculosis

摘要

Polymyositis and dermatomyositis are idiopathic inflammatory myopathies. Various antibodies have been identified as associated with polymyositis/dermatomyositis, and characteristic phenotypes have been reported for each.2,3 Anti-melanoma differentiation-associated gene 5 (MDA-5) antibody is associated with rapid progressive interstitial pneumonia, and cases with high ferritin are reported to have an extremely poor prognosis.4,5 We report a case of simultaneous onset of anti-MDA-5 antibody-positive dermatomyositis accompanied by interstitial pneumonia and pulmonary tuberculosis.