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Massive mandibular destruction and alveolar nerve infiltration without lower lip paresthesia in primary intraosseous carcinoma: Report of two cases and critical appraisal of diagnostic criteria

机译:巨大的下颌破坏和肺泡神经渗透,没有初级骨髓癌的唇唇痛:两种情况的报告和诊断标准的批判性评估

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Objective: To report two cases of solid type primary intraosseous carcinoma (PIOC) with a critical appraisal of one of the WHO diagnostic criteria. Summary: Both patients had radiographic and histopathologic findings showing massive mandibular destruction as well as the involvement of the inferior alveolar nerve, without lip or chin paresthesia. Patients were treated through hemimandibulectomy followed by reconstruction through fibula free flap and forearm flap. Conclusion: Lip and/or chin paresthesia are rather frequent in metastatic and salivary gland tumors but not in primary tumors of the jaws. Reasons for such a discrepancy are mostly unknown. A few hypotheses are put forward here. It is the opinion of the authors that most of the diagnostic criteria for solid type PIOC are acceptable. However, the criterion "absence of ulcer formation on the overlying mucosa" mainly depends on the dimension of the tumor at diagnosis.
机译:目的:报告两种固体初级鼻内癌(PIOC)的诊断标准之一的批判性评价。 发明内容:两种患者都有射线照相和组织病理学发现,显示巨大的下颌破坏以及较小的肺泡神经的累积,没有唇或下巴。 患者通过Hemimandibul切除术治疗,然后通过腓骨自由瓣和前臂皮瓣重建。 结论:唇缘和/或下巴患者在转移和唾液腺肿瘤中常常频繁,但不在颌骨的原发性肿瘤中。 这种差异的原因大多是未知的。 这里提出了一些假设。 作者认为大多数固体型PIOC的诊断标准是可接受的。 然而,“覆盖粘膜上没有溃疡形成的标准”主要取决于肿瘤在诊断时的尺寸。

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