Epigenetic Control of Haematopoietic Stem Cell Aging and Its Clinical Implications

Choudry Fizzah Aziz; Frontini Mattia

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Epigenetic Control of Haematopoietic Stem Cell Aging and Its Clinical Implications

机译：呕血干细胞老化的表观遗传控制及其临床意义

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Aging, chronic inflammation, and environmental insults play an important role in a number of disease processes through alterations of the epigenome. In this review we explore how age-related changes in the epigenetic landscape can affect heterogeneity within the haematopoietic stem cell (HSC) compartment and the deriving clinical implications.

机译：衰老，慢性炎症和环境损伤在多种疾病过程中发挥着重要作用，通过外观蛋白酶的改变。在本次综述中，我们探讨了表观遗传景观中的年龄相关变化可以影响血液生成干细胞（HSC）隔室内的异质性和导出的临床意义。

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《Stem cells international》 |2016年第1期|共9页
作者
Choudry Fizzah Aziz; Frontini Mattia;
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Univ Cambridge Dept Haematol Cambridge CB2 0PT England;

Univ Cambridge Dept Haematol Cambridge CB2 0PT England;

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正文语种 eng
中图分类生物工程学（生物技术）;
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1. Epigenetic Control of Haematopoietic Stem Cell Aging and Its Clinical Implications [J] . Fizzah AzizChoudry, MattiaFrontini Stem cells international . 2016,第3期

机译：造血干细胞衰老的表观遗传控制及其临床意义
2. Prevention and management of BK-virus associated haemorrhagic cystitis in children following haematopoietic stem cell transplantation--a systematic review and evidence-based guidance for clinical management. [J] . Harkensee C, Vasdev N, Gennery AR, British Journal of Haematology . 2008,第5期

机译：造血干细胞移植后儿童BK病毒相关性出血性膀胱炎的预防和管理-系统评价和循证临床治疗指南。
3. Epigenetic regulation of cancer stem cells in liver cancer: current concepts and clinical implications. [J] . Marquardt JU, Factor VM, Thorgeirsson SS Journal of Hepatology: The Journal of the European Association for the Study of the Liver . 2010,第3期

机译：肝癌中癌症干细胞的表观遗传学调控：当前概念和临床意义。
4. Precession-based control methodology for haematopoietic stem cells harvesting [C] . Tang K.Z., Rauff M., Tan H.C., IEEE International Conference on Control and Automation . 2013

机译：基于进动的造血干细胞收获控制方法
5. Cadmium and aluminum alter epigenetically controlled histone modification pathways in mouse embryonic stem cells. [D] . Gadhia, Sanket R. 2015

机译：镉和铝改变小鼠胚胎干细胞中表观遗传控制的组蛋白修饰途径。
6. Epigenetic Control of Haematopoietic Stem Cell Aging and Its Clinical Implications [O] . Fizzah Aziz Choudry, Mattia Frontini 2016

机译：造血干细胞衰老的表观遗传控制及其临床意义
7. Epigenetic Control of Haematopoietic Stem Cell Aging and Its Clinical Implications [O] . Choudry Fizzah Aziz, Frontini Mattia 2015

机译：造血干细胞衰老的表观遗传控制及其临床意义

Epigenetic Control of Haematopoietic Stem Cell Aging and Its Clinical Implications

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