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首页> 外文期刊>Sadhana: Academy Proceedings in Engineering Science >Investigations for mechanical properties and biocompatibility of SS-316L implant prepared as rapid investment casting for batch production
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Investigations for mechanical properties and biocompatibility of SS-316L implant prepared as rapid investment casting for batch production

机译:SS-316L植入物的机械性能和生物相容性的研究制备为批量生产的快速投资铸造

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摘要

In this work, a detailed procedure for the development of biomedical implant (SS-316L) by combining fused deposition modeling (FDM), chemical vapor smoothing (CVS), silicon molding (SM) and investment casting (IC) for batch production has been outlined. In spite of being biocompatible and bioactive within the body, the implant must possess good surface quality and dimensional accuracy along with sufficient hardness in order to reduce the wear inside the body. So in this research work, investigations have been made on the surface finish, dimensional accuracy and hardness of the implants by varying two controllable factors of the IC process (drying time of primary coating and mould thickness). The tolerance grades for the selected dimension of the casted implants were within the allowable range as defined in UNI EN 20286-I (1995) standard of ISO. The process capability indices (C-p and C-pk) values greater than 1.33 for the surface hardness and radial dimension indicated that the proposed process is statistically controlled. Further, in order to evaluate the biocompatibility, an in vitro study was conducted to ensure the attachment of mouse embryonic fibroblasts cells (NIH-3T3) to the casted samples. The results of invitro study indicated that samples were capable of supporting cell adhesion and cell proliferation and hence can be used for tissue engineering.
机译:在这项工作中,通过组合融合沉积建模(FDM),化学蒸汽平滑(CVS),硅模制(SM)和投资铸件(IC)进行批量生产的详细方法,进行了生物医学植入物(SS-316L)的详细程序概述了。尽管在身体内生物相容性和生物活性,但植入物必须具有良好的表面质量和尺寸精度以及足够的硬度,以减少体内的磨损。因此,在这项研究工作中,通过改变IC工艺的两个可控因素(初级涂层的干燥时间和模具厚度)来对植入物的表面光洁度,尺寸精度和硬度进行研究。铸造植入物的所选尺寸的公差等级在ISO的UNI EN 20286-I(1995)标准中所定义的允许范围内。对于表面硬度和径向尺寸的工艺能力指数大于1.33的值,表明所提出的过程在统计上控制。此外,为了评估生物相容性,进行体外研究以确保小鼠胚胎成纤维细胞(NIH-3T3)与浇铸样品的附着。 invitro研究结果表明,样品能够支持细胞粘附和细胞增殖,因此可用于组织工程。

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