Association of Histologic Chorioamnionitis With Perinatal Brain Injury and Early Childhood Neurodevelopmental Outcomes Among Preterm Neonates

摘要

(Abstracted from JAMA Pediatr 2018;172(6):534-541) Acute chorioamnionitis refers to the neutrophilic inflammation of the placental tissues thought to result from an ascending bacterial infection. It is considered a major factor associated with preterm birth and has been estimated to occur in 40% to 80% of preterm deliveries.