An investigation of crosstalk between Wnt/beta-catenin and transforming growth factor-beta signaling in androgenetic alopecia

摘要

Background: Wnt and transforming growth factor-beta (TGF-beta) signaling pathways are known to be involved in the pathogenesis of androgenetic alopecia (AGA). However, the way that Wnt and TGF-beta signaling is altered in patients with AGA and whether there exists a crosstalk between them in pathogenetic process of AGA remain unclear.