Full circle: From thrombolysis to PCI post-thrombolysis, to thrombolysis with PCI, to PCI alone to thrombectomy alone, to nanothrombolysis

摘要

I want to share with you this personal view, albeit extremely biased, on the history of revascularisation and acute myocardial infarction…a history that I saw unfold over the last decades. In 1979 we invited Peter Rentrop, the pioneer of intracoronary streptokinase for acute MI to the Thorax Center in Rotterdam and soon after we started using this treatment for our patients. In 1981, the Rotterdam group, under the leadership of Désiré Collen, published an article in The Lancet on the use of tissue plasminogen activator (TPa) derived from melanoma cells to dissolve a venous thrombosis in… - See more at: http://www.pcronline.com/eurointervention/57th_issue/171/#sthash.so27jBIo.dpuf