Reply letter to the editor

摘要

We thank the authors for their interest in our article (1) and for their comments. Most of the literature to date regarding placental mesenchymal dysplasia (PMD) relates to cases of PMD that have surpassed the first trimester.As we indicated in our article, we believe that the detection rate of PMD was not underestimated in our institution, in part due to the fact that cases such as molar or suspected molar change are examined in great detail and are therefore carefully evaluated and distinguished from other pathologies, such as hydropic degeneration and PMD. In our institution, all first-trimester pregnancy losses from which placental or fetal tissue is obtained do indeed undergo histo-logical review; in cases where prior placental anomalies have been noted by ultrasound, this information is generally made available to the pathologists also.