Super resolution microscopy

摘要

On 10 December 2014, the Nobel Prize in Chemistry was given to Stefan Hell (Max Planck Heidelberg), William E. Moerner (Stanford University) and Eric Betzig (Howard Hughes Jenalia Research Farm) 'for the development of super-resolved fluorescence microscopy'. In the February issue (p. 14), we looked at the development of the light microscope and the contribution of W.E. Moerner, who was the first person (1989) to show that it was possible to detect single molecules. WE.'s research has spanned the areas of spectral hole-burning for optical storage, mechanisms of photorefractivity in organic materials, single-molecule spectroscopy and super-resolution microscopy.