A pilot study of subthalamic theta frequency deep brain stimulation for cognitive dysfunction in Parkinson's disease

Katherine W. Scangos; Cameron S. Carter; Gene Gurkoff; Lin Zhang; Kiarash Shahlaie

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A pilot study of subthalamic theta frequency deep brain stimulation for cognitive dysfunction in Parkinson's disease

机译：帕金森病的认知功能障碍次粒子近段频率深脑刺激的试验研究

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Highlights ? A first look at effect of deep brain stimulation frequency on executive control. ? 5 Hz, but not 130 Hz, stimulation of the subthalamic nucleus improved control. ? 2 days of continuous 5 Hz stimulation did not lead to significant habituation. ? 5 Hz stimulation in cognitive-emotion region of the subthalamic nucleus was safe. ? 5 Hz corticostriatal stimulation may restore task specific oscillatory activity.

机译：强调？第一次看深脑刺激频率对行政控制的影响。还 5Hz，但不是130赫兹，刺激亚饱和核改善控制。还 2天连续5 Hz刺激不会导致显着的习惯。还在亚饱和核的认知情绪区域中，5 Hz刺激是安全的。还 5 Hz皮质棘状刺激可以恢复任务特定的振荡活动。

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《Brain stimulation》 |2018年第2期|共3页
作者
Katherine W. Scangos; Cameron S. Carter; Gene Gurkoff; Lin Zhang; Kiarash Shahlaie;
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作者单位

Department of Psychiatry University of California Davis UC Davis Imaging Research Center;

Department of Psychiatry University of California Davis UC Davis Imaging Research Center;

Department of Neurological Surgery University of California;

Department of Neurology University of California Davis Lawrence J. Ellison Ambulatory Care Center;

Department of Neurological Surgery University of California;

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原文格式 PDF
正文语种 eng
中图分类诊断学;
关键词
DBS cognition STN; Executive control; Depression; Theta frequency; DBS stimulation paradigm;

机译：DBS认知STN;行政控制;抑郁症;θ频率;DBS刺激范式;

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1. A pilot study of subthalamic theta frequency deep brain stimulation for cognitive dysfunction in Parkinson's disease [J] . Katherine W. Scangos, Cameron S. Carter, Gene Gurkoff, Brain stimulation . 2018,第2期

机译：帕金森病的认知功能障碍次粒子近亲近脑刺激的试验研究
2. Simultaneous low-frequency deep brain stimulation of the substantia nigra pars reticulata and high-frequency stimulation of the subthalamic nucleus to treat levodopa unresponsive freezing of gait in Parkinson's disease: A pilot study [J] . Valldeoriola Francesc Parkinsonism & related disorders . 2019,第期

机译：同时低频深脑刺激真实性的NIGRA映射皮划艇和高频刺激的亚氨基氨核，以治疗帕金森病的步态无响应冻结：试点研究
3. Simultaneous low-frequency deep brain stimulation of the substantia nigra pars reticulata and high-frequency stimulation of the subthalamic nucleus to treat levodopa unresponsive freezing of gait in Parkinson's disease: A pilot study [J] . Valldeoriola Francesc, Munoz Esteban, Rumia Jordi, Parkinsonism & related disorders . 2019,第期

机译：同时低频深脑刺激真实性的NIGRA映射皮划艇和高频刺激的亚氨基氨核，以治疗帕金森病的步态无响应冻结：试点研究
4. A new biomarker for closed-loop deep brain stimulation in the subthalamic nucleus for patients with Parkinson's disease [C] . Gmel Gerrit E., Parker John L., Hamilton Tara J. IEEE biomedical circuits and systems conference . 2014

机译：帕金森氏病患者丘脑下核闭环深部脑刺激的新生物标记
5. Effect of low frequency bilateral deep brain stimulation of subthalamic nucleus on balance and gait in Parkinson disease [D] . Vallabhajosula, Srikant 2010

机译：低频双侧丘脑底核深部脑刺激对帕金森病患者平衡和步态的影响
6. Pilot Study Assessing the Feasibility of Applying Bilateral Subthalamic Nucleus Deep Brain Stimulation in Very Early Stage Parkinsons Disease: Study design and rationale [O] . David Charles, Christopher Tolleson, Thomas L. Davis, -1

机译：试点研究评估在早期帕金森病中施加双侧次粒细胞核深脑刺激的可行性：研究设计和理由
7. Cognitive effects of theta frequency bilateral subthalamic nucleus stimulation in Parkinson’s disease: A pilot study [O] . Jordan Lam, Justin Lee, Marcus Williams, 2021

机译：帕金森病中雷达频次次肾细胞核刺激的认知效应：试验研究
8. Statistical Power of Studies Examining the Cognitive Effects of Subthalamic Nucleaus Deep Brain Stimulation in Parkinson's Disease. [R] . Woods, S. P., Rippeth, J. D., Conover, E., 2006

机译：研究统计学研究对丘脑底核深部脑刺激对帕金森病的认知影响。

A pilot study of subthalamic theta frequency deep brain stimulation for cognitive dysfunction in Parkinson's disease

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