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Topical treatment of psoriasis.

机译:牛皮癣的局部治疗。

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Topical therapy forms the cornerstone in the management of psoriasis. Of significant value as monotherapy in mild to moderate psoriasis, it is used predominantly as adjunctive therapy in moderate and severe forms of the disease. Over the past decade, topical treatment of psoriasis has evolved from the age-old applications of tar and dithranol to the more acceptable and efficacious options of topical corticosteroids, retinoids and vitamin D analogues, with the advent of a wide range of appropriately tailored vehicles and sophisticated delivery modes. To ensure therapeutic success, proper patient education about the disease, the treatment options, their specific application modality and adverse effects is essential. This will help alleviate the common problem of poor patient adherence, and inevitably result in more optimal clinical outcomes.
机译:局部治疗是牛皮癣治疗的基石。在轻度至中度牛皮癣中,单药治疗具有重要价值,主要用于中度和重度疾病的辅助治疗。在过去的十年中,牛皮癣的局部治疗已从焦油和二乙醇的古老应用演变为局部使用皮质类固醇,类维生素A和维生素D类似物的更可接受和有效的选择,并出现了各种适当定制的载体和复杂的投放模式。为了确保治疗成功,必须对患者进行适当的有关疾病,治疗选择,其具体应用方式和不良反应的教育。这将有助于减轻患者依从性差的常见问题,并不可避免地导致更理想的临床结果。

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