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Hypertension: a new look at an old problem.

机译:高血压:从新角度看老问题。

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摘要

PURPOSE OF REVIEW: This review reports the specific impact that hypertension, identified by its component subtype classification, has on perioperative outcomes. Most importantly, we review the risk of systolic hypertension and pulse pressure hypertension independent of elevated diastolic blood pressure on patients undergoing cardiac surgery. RECENT FINDINGS: Systemic hypertension is identified as a major risk factor for cardiovascular morbidity in most larger population-based studies. Nearly a third of the population in the United States has or will have some form of hypertension disease, with many under-diagnosed or under-treated. Classification of hypertensive subtypes has been well recognized as an important component for risk stratification in the ambulatory population in recent years, but remains poorly recognized in the surgical setting. We present recent data unveiling the importance of pulse pressure above that of systolic and diastolic pressures. SUMMARY: The evidence is compelling that wide pulse pressure hypertension is a strong and an independent predictor of adverse perioperative renal, cerebral and mortality outcomes. We discuss the physiology for this important novel observation in an acute surgical patient population and provide an explanation.
机译:审查的目的:这项审查报告高血压,其组成亚型分类确定,对围手术期结局的具体影响。最重要的是,我们回顾了接受心脏手术的患者的收缩压和脉压性高血压的风险,与舒张压升高无关。最新发现:在大多数基于人群的研究中,系统性高血压被认为是心血管疾病的主要危险因素。在美国,近三分之一的人口患有或将患有某种形式的高血压疾病,其中许多疾病的诊断或治疗不足。近年来,高血压亚型的分类已被公认为是非卧床人群风险分层的重要组成部分,但在外科手术环境中仍知之甚少。我们目前的最新数据揭示了脉压高于收缩压和舒张压的重要性。摘要:证据令人信服,广泛的脉压性高血压是围手术期不良肾,脑和死亡率结局的强有力的独立预测因子。我们讨论了这一重要的新颖性观察在急性外科手术患者群体中的生理学,并提供了解释。

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