Efficient Copper-Catalyzed N-Arylation of Amides and Imidazoles with Aryl Iodides

摘要

The C-N cross-coupling of amides and imidazoles with aryl iodides is described using Cul in tetrabutylammonium bromide (TBAB) under ligand-free conditions. The reaction is simple, general, and efficient affording the C-N cross-coupled products in shorter time and in high yield.