Correlations were tested using the Fisher exact test and differences between SpO levels were analyzed using an independent, 2-sided t test at a significance level of P< .05; JMP version 8.0.2 statistical software was used (SAS Institute Inc). The study was approved by the ethics committee of the University of Tubingen; all participants gave written informed consent. Results. Retinal abnormalities were not noted at baseline in any of the participants. At high altitude, marked bilateral leakage of peripheral retinal vessels was observed in 7 of 14 participants (50%; Figure 1). Leakage uniformly occurred in the following distinct pattern: always present in the temporal-inferior and absent in the nasal-superior periphery (Figure 2), favoring venules more than arterioles. Staining of the optic disc was detected in 57% (8/14); no leakage was found in the central retina (Figure 2).All findings completely reversed after descent (Figure 1). Incidence of AMS at high altitude was 50% (7/14).
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机译：相关关系使用Fisher精确检验进行检验，SpO水平之间的差异使用独立的2面t检验分析，显着性水平为P <.05;使用了JMP版本8.0.2统计软件（SAS Institute Inc）。该研究得到了图宾根大学伦理委员会的批准;所有参与者均签署了知情同意书。结果。基线时未发现任何参与者的视网膜异常。在高海拔地区，在14位参与者中有7位观察到了视网膜视网膜血管明显的双侧渗漏（50％;图1）。泄漏均匀地发生在以下不同的模式中：始终存在于颞下，而不存在于鼻上周边（图2），比小动脉更易吸引小静脉。视盘的染色率为57％（8/14）;在视网膜中央没有发现渗漏（图2），下降后所有发现都完全相反（图1）。高海拔地区AMS的发生率为50％（7/14）。
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