Editorial comment

摘要

Obese men are at high risk for prostate cancer death and, although they have a larger prostate, they have lower PSA.These authors examined the relationship between adiposity components, PV, anthropometries and PSA in a cross-section of Korean men. Although the generalizability of these findings in other races requires confirmation, the authors further our understanding of the obesity-PSA relationship by validating the hemodilution theory. More importantly, since BMI does not factor in specific measures of adiposity, these results offer insight into the role of adiposity, particularly visceral adiposity, as a potential driving factor for larger PV and PSA production. This is in contrast to subcutaneous adiposity, which along with other surrogates of obesity were associated with decreased PSA.