Re: Why do our colleagues still image for cryptorchidism? Ignoring the evidence: J. S. Elder. J Urol 2011; 185: 1566-1567.

摘要

We would also like to comment on the predictive ability of other biomarkers regarding renal scarring, such as procalcitonin. Indeed, about 12 different teams have shown that procalcitonin provides a good predictive ability for diagnosing renal parenchymal involvement. These findings have also been confirmed in meta-analyses of studies and individual patient data.2'3 Moreover, procalcitonin was confirmed to offer diagnostic accuracy for late renal scarring in 9 cohort studies also summarized in a meta-analysis.3 Pooling individual patient data allowed us to perform a comparison of CRP, white blood cell count and procalcitonin, which revealed that procalcitonin was a better predictor than CRP or white blood cell count regarding acute pyelonephritis and later renal damage, with an area under the ROC curve that was significantly higher for both conditions.3 However, procalcitonin is not often used in daily clinical practice because of its poor availability in the context of emergency care.