EDITORIAL COMMENT

摘要

These authors report that peripubertal boys with a history of hypospadias and cryptorchidism had higher FSH than normal boys and those with isolated cryptorchidism or hypospadias. FSH was independent of hypospadias severity, testicular site and unilateral vs bilateral cryptorchidism. These results contrast with those in prior reports that bilateral and nonpalpable testes are more likely to be associated with higher FSH, decreased paternity and more severe testicular histopathol-ogy.As they note, the conclusions are limited by the small sample size and the confounding introduced by combining patients with different hypospadias severities, and unilateral and bilateral cryptorchid-ism into the same group. Furthermore, to our knowledge the clinical significance and ability of peripu-bertal FSH to predict infertility is unknown.