For more than 60 years it has been widely accepted that T administration causes PCa growth or adds fuel to the fire (reference 16 in article). In this study 13 symptomatic men with TD and untreated PCa received testosterone therapy for a mean of 2.5 years. In this small cohort of men (mean age approximately 59 years) posttreatment biopsies revealed no change in prostate volume or PSA and no definite cancer progression in any man. No cancer was found in 54% of followup biopsies. These results suggest this is a seminal article, requiring further validation and elaboration.
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