These authors examined latent PC a in the autopsy specimens of men who died of causes other than PCa and found a similar prevalence of subclinical cancer in AAM and EAM. This is juxtaposed to data from the Detroit SEER registry showing a higher rate of advanced/metastatic PCa in AAM.Although their contention that PCa grows more rapidly and transforms earlier from latent to aggressive disease in AAM requires validation, it is undisputed that AAM bear a greater PCa burden. Thus, we must ask why and what can be done? Regarding the former, the likely explanation is complex, including genetic predisposition, socioeconomic disparity, lifestyle variations, and less aggressive screening and treatment.
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