A nonlocal harmonic elastic rod model is proposed to describe the elastic behavior of short DNA molecules. We show that the nonlocal interactions contribute to effective bending energy of the molecule and affect its apparent persistence length. It is also shown that the anomalous behavior which has been observed in all-atom molecular dynamic simulations [A. K. Mazur, Biophys. J. 134, 4507 (2006)] can be a consequence of both nonlocal interactions between DNA base pairs and the intrinsic curvature of DNA.
展开▼
机译：提出了一种非局部谐波弹性杆模型来描述短DNA分子的弹性行为。我们表明，非局部相互作用有助于分子的有效弯曲能并影响其表观持久性长度。还显示了在全原子分子动力学模拟中观察到的异常行为[A． K. Mazur，生物物理。 J. 134，4507（2006）]可能是DNA碱基对之间非局部相互作用和DNA固有曲率的结果。
展开▼
