1-(4-nitrophenoxycarbonyl)-7-pyridin-4-yl indolizine: a new versatile fluorescent building block. Application to the synthesis of a series of fluorescent beta-cyclodextrins

摘要

The synthesis of a series of new fluorescent building blocks 1a-d incorporating a pyridinoindolizine unit and two potentially reactive sites is described. The reaction of 1a-d with the mono-6-amino-6-deoxy-beta-cyclodextrin provides the corresponding fluorescent water soluble hosts 2a-d in good yield. The sensor properties of 2a-d in the presence of 1-adamantanol is described. (c) 2005 Elsevier Ltd. All rights reserved.