Editorial comment

摘要

Thus, the emerging concerns of increased fluoroquinolone resistance have been amplified by the increased prevalence of more virulent clonal phenotypes. Clearly, further studies will be needed to better define risk factors for and clinical consequences of colonization with fluoroquinolone-resistant E coli and, in particular, with what appears to be the dominant lineage of E coli ST131. Because of these implications, empiric prophylaxis with ciprofloxacin is rapidly becoming a major concern, and alternatives, such as treatment with directed prophylaxis based on prebiopsy rectal swab cultures, should be considered.