Combination of adipose-derived mesenchymal stem cells (ADMSC) and ADMSC-derived exosomes for protecting kidney from acute ischemia-reperfusion injury

Lin Kun-Chen; Yip Hon-Kan; Shao Pei-Lin; Wu Shun-Cheng; Chen Kuan-Hung; Chen Yen-Ta; Yang Chih-Chao; Sun Cheuk-Kwan; Kao Gour-Shenq; Chen Sheng-Yi; Chai Han-Tan; Chang Chia-Lo; Chen Chih-Hung; Lee Mel S.

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Combination of adipose-derived mesenchymal stem cells (ADMSC) and ADMSC-derived exosomes for protecting kidney from acute ischemia-reperfusion injury

机译：脂肪间充质干细胞（ADMSC）和ADMSC衍生的外泌体的组合，以保护肾脏免受急性缺血-再灌注损伤

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Background: In this study, we tested the hypothesis that a combined adipose-derived mesenchymal stem cell (ADMSC) and ADMSC-derived exosome therapy protected rat kidney from acute ischemia-reperfusion (IR) injury (i.e., ligation of both renal arteries for 1 h and reperfusion for 72 h prior to euthanization).

机译：背景：在这项研究中，我们测试了以下假设：脂肪衍生的间充质干细胞（ADMSC）和ADMSC衍生的外泌体联合治疗可保护大鼠肾脏免受急性缺血再灌注（IR）损伤（即，两个肾动脉结扎1次）小时并在安乐死之前再灌注72小时）。

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《International Journal of Cardiology》 |2016年第null期|共13页
作者
Lin Kun-Chen; Yip Hon-Kan; Shao Pei-Lin; Wu Shun-Cheng; Chen Kuan-Hung; Chen Yen-Ta; Yang Chih-Chao; Sun Cheuk-Kwan; Kao Gour-Shenq; Chen Sheng-Yi; Chai Han-Tan; Chang Chia-Lo; Chen Chih-Hung; Lee Mel S.;
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正文语种 eng
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Acute kidney ischemia-reperfusion injury; Exosome; Adipose-derived mesenchymal stem cell; Inflammation; Oxidative stress;

机译：急性肾脏缺血再灌注损伤;外来体;脂肪来源的间充质干细胞;炎症;氧化应激;

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1. Combination of adipose-derived mesenchymal stem cells (ADMSC) and ADMSC-derived exosomes for protecting kidney from acute ischemia-reperfusion injury [J] . Lin Kun-Chen, Yip Hon-Kan, Shao Pei-Lin, International Journal of Cardiology . 2016,第Null期

机译：脂肪衍生的间充质干细胞（ADMSC）和ADMSC衍生的外泌体，用于保护肾脏免受急性缺血再灌注损伤的保护
2. Adipose-Derived Mesenchymal Stem Cell Protects Kidneys against Ischemia-Reperfusion Injury through Suppressing Oxidative Stress and Inflammatory Reaction [J] . Yen-Ta Chen, Cheuk-Kwan Sun, Yu-Chun Lin, Journal of Translational Medicine . 2011,第1期

机译：脂肪间充质干细胞通过抑制氧化应激和炎症反应，保护肾脏免受缺血再灌注损伤。
3. Synergistic effect of combined melatonin and adipose-derived mesenchymal stem cell (ADMSC)-derived exosomes on amelioration of dextran sulfate sodium (DSS)-induced acute colitis [J] . Chia-Lo Chang, Chih-Hung Chen, John Y Chiang, American Journal of Translational Research . 2019,第5期

机译：褪黑素与脂肪间充质干细胞（ADMSC）联合的外泌体的协同作用对硫酸右旋糖酐钠（DSS）引起的急性结肠炎的缓解作用
4. A Combination of Ultrasound Targeted Microbubble Destruction with Transplantation of Bone Marrow Mesenchymal Stem Cells Promotes Recovery of Acute Liver Injury [C] . Ting Sun, Fan Li IEEE International Ultrasonics Symposium . 2018

机译：超声靶向微泡破坏与骨髓间充质干细胞移植的结合促进急性肝损伤的恢复
5. Comparison of Platelet-rich Plasma, Bone Marrow Mesenchymal Stem Cells, Adipose-derived Mesenchymal Stem Cells, and Placebo in the Treatment of Knee Osteoarthritis [D] . Bach, Oscar. 2020

机译：富含血小板血浆，骨髓间充质干细胞，脂肪衍生间充质干细胞，安慰剂治疗膝关节骨关节炎的比较
6. Intravenous administration of xenogenic adipose-derived mesenchymal stem cells (ADMSC) and ADMSC-derived exosomes markedly reduced brain infarct volume and preserved neurological function in rat after acute ischemic stroke [O] . Kuan-Hung Chen, Chih-Hung Chen, Christopher Glenn Wallace, 2016

机译：静脉注射异种脂肪来源的间充质干细胞（ADMSC）和ADMSC来源的外来体可显着减少急性缺血性中风后大鼠的脑梗死体积并保留神经功能
7. P2565Combination of adipose-derived mesenchymal Stem Cells (ADMSC) and ADMSC-derived exosomes for protecting kidney from acute ischemia-reperfusion injury [O] . S. Chua, P.L. Shao, P.H. Sung, 2017

机译：P2565脂肪衍生的间充质干细胞（ADMSC）和ADMSC衍生的外泌体，用于保护肾脏免受急性缺血再灌注损伤的保护

Combination of adipose-derived mesenchymal stem cells (ADMSC) and ADMSC-derived exosomes for protecting kidney from acute ischemia-reperfusion injury

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