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Sensitive skin: closing in on a physiological cause

机译:敏感性皮肤:因生理原因而关闭

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The phenomenon of 'sensitive skin' is a relatively recent complaint in which certain individuals report more intense and frequent adverse sensory effects than the normal population upon use of cosmetic (personal-care) products. Originally defined as a minority complaint, sensitive skin is now claimed by a majority of women in industrialized countries and nearly half of men. Sensitive skin is self-diagnosed and typically unaccompanied by any obvious physical signs of irritation, and the number of individuals who claim sensitivity has risen steadily with the number of consumer products targeted towards this supposedly uncommon group. Believed by many dermatologists, therefore, to be a 'princess and the pea' phenomenon, the problem of sensitive skin has largely avoided focussed research. Over the last few years, however, the evidence of documentable biophysical changes associated with the largely sensory symptoms of this disorder has accumulated, including some gained by improved methods of identifying subclinical signs of skin irritation. Although the understanding of the aetiology of this phenomenon is as yet incomplete, existing research now supports a biophysical origin for this disorder. Effective methods of diagnosis, intrinsic and extrinsic contributors to exaggerated neural sensitivity, and the specific mechanisms of the discomfort associated with the compliant are required, as are appropriate means of prevention and treatment.
机译:“敏感性皮肤”现象是相对较新的抱怨,其中某些人在使用化妆品(个人护理)产品时报告称其感觉感觉比正常人群更为强烈和频繁。最初被定义为少数群体投诉,但在工业化国家中,大多数女性和近一半的男性声称拥有敏感皮肤。敏感性皮肤是自我诊断的,通常不伴有任何明显的刺激性体征,声称针对敏感性的个体数量与针对这个据称罕见的人群的消费产品数量稳步上升。因此,许多皮肤科医生认为这是“公主与豌豆”现象,因此敏感性皮肤问题在很大程度上避免了集中研究。然而,在过去的几年中,与该疾病的大部分感官症状相关的可记录的生物物理变化的证据已经积累,包括通过改进识别皮肤刺激性亚临床体征的方法获得的证据。尽管对这种现象的病因学的理解还不完全,但是现有的研究现在支持这种疾病的生物物理起源。需要有效的诊断方法,内在和外在因素导致过度的神经敏感性,以及与顺应性相关的不适的具体机制,这是预防和治疗的适当手段。

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