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首页> 外文期刊>Clinical cardiology. >Swallowing-induced atrial tachyarrhythmia triggered by salbutamol: case report and review of the literature.
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Swallowing-induced atrial tachyarrhythmia triggered by salbutamol: case report and review of the literature.

机译:沙丁胺醇引发吞咽引起的房性心律失常:病例报告和文献复习。

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摘要

CASE: A 49-year-old patient experienced chest discomfort while swallowing. On electrocardiogram, episodes of atrial tachyarrhythmia were recorded immediately after swallowing; 24-hour Holter monitoring recorded several events. The arrhythmia resolved after therapy with atenolol, but recurred a year later. The patient noticed that before these episodes he had been using an inhalator of salbutamol. After stopping the beta-agonist, and after a week with the atenolol, the arrhythmia disappeared. DISCUSSION: Swallowing-induced atrial tachyarrhythmia (SIAT) is a rare phenomenon. Fewer than 50 cases of SIAT have been described in the literature. This article summarizes all the cases published, creating a comprehensive review of the current knowledge and approach to SIAT. It discusses demographics, clinical characteristics and types of arrhythmia, postulated mechanisms of SIAT, and different treatment possibilities such as medications, surgery, and radiofrequency catheter ablation (RFCA). CONCLUSION: Salbutamol is presented here as a possible trigger for SIAT. Although it is difficult to define causality in a case report, it is logical to think that a beta-agonist like salbutamol (known to induce tachycardia) may be the trigger of adrenergic reflexes originating in the esophagus while swallowing and that a beta-blocker such as atenolol (that blocks the adrenergic activity) may relieve it.
机译:病例:一名49岁的患者吞咽时出现胸部不适。在心电图上,吞咽后立即记录出房性心律失常的发作。 24小时动态心电图监测记录了几起事件。使用阿替洛尔治疗后心律失常得以缓解,但一年后复发。病人注意到在这些发作之前,他一直在使用沙丁胺醇吸入器。停止使用β-激动剂后,和使用阿替洛尔一周后,心律失常消失。讨论:吞咽引起的房性心律失常(SIAT)是一种罕见的现象。文献中描述的少于50例SIAT病例。本文总结了所有已发布的案例,对SIAT的当前知识和方法进行了全面回顾。它讨论了人口统计学,心律失常的临床特征和类型,SIAT的假定机制以及药物,手术和射频导管消融(RFCA)等不同的治疗可能性。结论:沙丁胺醇可能是引发SIAT的诱因。尽管很难在病例报告中定义因果关系,但合乎逻辑的是认为像沙丁胺醇这样的β激动剂(已知会引起心动过速)可能是吞咽时源自食道的肾上腺素反射的触发因素,而β受体阻滞剂因为阿替洛尔(阻止肾上腺素能活动)可以缓解它。

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