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Inhalability of large solid particles

机译:大颗粒固体的吸入性

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Large particles (10-150 #mu#m) with systemic toxicity pose a health risk if inhaled regardless of where they deposit. This research seeds to better define particle inhalability, the fraction of airborne particles that are ihaled as a function of particle size. Measurements of inhalability were made for solid particles using a 1.6 X 1.6 X 5-m wind tunnel. Tunnel air velocities were 0.4, 1.0, and 1.6 m/s. A full-size, full-torso mannequin was used to collect dust entering either the mouth or nose for breating at minute volumes of 14.2, 20.8 , and 37.3 l. The mannquin either faced the oncoming wind or rotated slowly (0.06 rpm) rpm) during sample collection. At the test section, air velocity was uniform to within 10% and aerosol concentration was uniform to within 15% over the central 80% of the cross section. Orientation-averaged inhalability for mouth breathing was higher than the inhalable particlate mass (IPM) sampling criterion for particles smaller than 35 #mu#m and lower than the criterion for larger particles, leveling off at about 30% for particles > 70 #mu#m. Facing-the-wind mouth inhalability showed the same trend as the IPM sampling criterion, but the measured values were 25% higher. Wind velocity and breathing pattern had little effect on inhalability for the range of conditions examined here. Orientation-averaged inhalability for nose breathing dropped quickly with particle size reaching less than 10% at 60% #mu#m. Facing-the-wind nose inhalability was slightly increased for particles smaller than 60 #mu#m compared to orientation averaged inhalability for nose breathing.
机译:具有全身毒性的大颗粒(10-150#μm)无论吸入何处,都会造成健康危险。这项研究旨在更好地定义颗粒的可吸入性,即吸入的空气中颗粒的比例随颗粒大小而变化。使用1.6 X 1.6 X 5-m风洞测量了固体颗粒的可吸入性。隧道风速分别为0.4、1.0和1.6 m / s。使用全尺寸,全躯干的人体模型收集进入嘴或鼻子的粉尘,以每分钟14.2、20.8和37.3 l的体积繁殖。在样品采集过程中,人体模型要么面对迎面而来的风,要么缓慢旋转(0.06 rpm)rpm。在测试部分,在横截面的中央80%处,风速均匀地保持在10%以内,气溶胶浓度均匀地在15%以内。小于35#mu#m的颗粒的平均吸入口呼吸性高于可吸入颗粒物(IPM)采样标准,而小于较大颗粒的标准则低于平均颗粒吸入标准,对于大于70#mu#的颗粒,稳定在约30%米面对风的可吸入性与IPM采样标准显示出相同的趋势,但测量值高出25%。在这里检查的条件范围内,风速和呼吸方式对吸入性影响很小。鼻子呼吸的方向平均可吸入性迅速下降,在60%#mu#m时粒径小于10%。小于60#μ#m的颗粒,与面向鼻子呼吸的定向平均可吸入性相比,面向风的鼻子可吸入性略有增加。

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