Human Embryonic Stem Cells Contaminated

摘要

One solution to this obstacle might be to eliminate such animal products from cultures and instead use human serum and human-derived feeder cells. But there has been little success with such attempts, and the use of an "all-human" environment carries its own risks such as contamination with newly emerging padiogens, the investigators stated. In addition, it may be impossible to completely eliminate Neu5Gc, because it has become metabolically incorporated into the contaminated HESCs. The authors therefore suggest that it would be safest to obtain newly derived HESCs mat have never been exposed to any animal products. But "the current regulatory climate in the United States precludes this type of approach, when using federal grant dollars," they wrote.