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The healthy worker effect and nuclear industry workers

机译:健康工人效应与核工业工人

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The linear no-threshold (LNT) dose-effect relationship has been consistently used by most radiation epidemiologists to estimate cancer mortality risk. The large scattering of data by International Agency for Research on Cancer, IARC (Vrijheid et al. 2007; Therry-Chef et al. 2007; Cardis et al. 2007), interpreted in accordance with LNT, has been previously demonstrated (Fornalski and Dobrzyński 2009). Using conventional and Bayesian methods the present paper demonstrates that the standard mortality ratios (SMRs), lower in the IARC cohort of exposed nuclear workers than in the non exposed group, should be considered as a hormetic effect, rather than a healthy worker effect (HWE) as claimed by the IARC group.
机译:大多数放射线流行病学家一直使用线性无阈值(LNT)剂量效应关系来估计癌症死亡风险。 IARC国际癌症研究机构(Vrijheid等,2007; Therry-Chef等,2007; Cardis等,2007)对数据的大量散布,已根据LNT进行了证明(Fornalski和Dobrzyński) 2009)。使用常规方法和贝叶斯方法,本论文证明,在IARC暴露的核工作人员队列中,标准死亡率(SMR)低于未暴露组的标准死亡率,应被认为是一种激素效应,而不是健康的工作者效应(HWE) ),由IARC小组声明。

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