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首页> 外文期刊>Veterinary Ophthalmology >A case of conjunctival melanoma in a cat
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A case of conjunctival melanoma in a cat

机译:猫结膜黑色素瘤1例

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摘要

Abstract Since 1985, 5 cases of feline conjunctival melanoma have been reported in the literature. Information on feline conjunctival melanoma epidemiological features, localizations, macroscopic features and histological features is limited. We are describing the clinical, histopathologic features and outcomes in a cat that presented clinically with a slow developing dark brown mass located under the upper eyelid of the left eye. Pertinent literature is reviewed; and the recognizable clinical features and treatment are discussed. The mass was surgically resected. Despite its size, the lesion was easily separated from underlying tissues, making possible a macroscopic complete resection that left intact the adjacent conjunctiva. The tumour histological examination has showed a pigmented melanoma lacking encapsulation, but presenting a clear zone delimiting the lesion. It was exclusively composed of epithelioid cells, and presented mild cellular anaplasia and weak mitotic activity. These features allowed it to be classified as a quite differentiated melanoma with few signs of potential malignancy. In accordance with these histologic features, no recurrence has been registered 34 months after surgery. Thus, a favorable outcome is now reported for two out of six cases of conjunctival melanoma in the cat. This report also confirms the predilection for this neoplasm to arise from the bulbar conjunctiva.
机译:摘要自1985年以来,已有5例猫结膜黑色素瘤报道。关于猫结膜黑色素瘤流行病学特征,位置,宏观特征和组织学特征的信息有限。我们正在描述一只猫的临床,组织病理学特征和预后,该猫临床表现为位于左眼上眼睑下方的缓慢发展的暗褐色肿块。回顾了相关文献;并讨论了可识别的临床特征和治疗方法。肿块被手术切除。尽管其大小很大,但病变很容易从下面的组织中分离出来,从而可以进行宏观的完整切除,而保留邻近结膜的完整性。肿瘤组织学检查显示色素沉着的黑色素瘤缺乏包膜,但呈现出清晰的区域来界定病变。它仅由上皮样细胞组成,并表现出轻度的细胞发育不良和弱的有丝分裂活性。这些特征使其可以被归类为高度分化的黑色素瘤,几乎没有潜在的恶性迹象。根据这些组织学特征,手术后34个月未发现复发。因此,据报道,猫结膜黑色素瘤中有六分之二的病例有良好的预后。该报告还证实了这种肿瘤的好发源于结膜结膜。

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