RE: Hemolytic uremic syndrome outbreak in Turkey in 2011

摘要

To the Editor,We were pleased to read Dr. Ozsoylu's Letter to the Editor regarding our paper titled "Hemolytic uremic syndrome outbreak in Turkey in 2011"1 We would like to comment on two very important points that Ozsoylu made about Shiga toxin-producing Escherichia coli (STEC) hemolytic uremic syndrome (HUS).Rock et al. proposed that molecular similarities between membrane antigen CD36 and Shiga toxin lead to the development of antibodies, and it was this that caused the events in STEC-HUS in 2005. Since then, no other evidence of immune-mediated diseases has been reported in the pathophysiology of STEC-HUS.