Editorial comment

摘要

We appreciate Dr. Crook's excellent comments and agree on some points. First, retrospectively, it might have been more useful to permit a cluster of core biopsies (3 or 4) to be taken from the suspicious areas. However, because we restricted enrollment to patients with 1-cm suspicious lesions on erMRI, we thought that the stringent requirement of 1 biopsy would be offset by the lesion size. However, if this technique were to be used for focal therapy, treating a relatively larger volume of gland, even if not affected by PCa, would be unlikely to be harmful and approximation of the target not problematic, because there would be no need to spare the normal prostate gland.