Histotripsy is a method of ultrasound therapy that uses intense bursts of ultrasound to destroy tissue by cavitation rather than thermal mechanisms. The aim of this study is to develop his-totripsy as a noninvasive (potentially office based) therapy for the treatment of benign prostatic hyperplasia (BPH) with equivalent efficacy to transurethral resection of the prostate and a more favorable side effect profile.
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