Systematic evaluation and Meta-analysis of acupuncture and collaterals cupping therapy for Knee Osteoarthritis

摘要

Objective In order to obtain the best treatment program for Knee Osteoarthritis (KOA), to alleviate the pain of patients with KOA, and to systematically evaluate the efficacy of acupuncture cupping therapy for KOA. Methods we used computer to search the databases of CNKI (1989-2018.10), Wanfang (1989-2018.10), VIP (1989-2018.10), PubMed (1966-2018.10), EMbase (1986-2018.10) and Cochrane Library (the 3rd issue of 2018). And the literature quality was evaluated by Jadad scale. Results A total of 19 eligible RCT studies were included, and a total of 2,088 patients participated in the eligible clinical study. Meta-analysis results showed that the total effective rate OR combination =2.85[OR =3.98, 95%CI (2.98,5.32), P 0.00001]. The results showed that the curative effect of acupuncture and collaterals cupping in the treatment of KOA was superior to other therapies. Conclusion Acupuncture and cupping therapy of traditional Chinese medicine is effective and safe in treating KOA. Due to the impact of the original study on Meta-analysis results, more large samples and high-quality clinical trials are still needed to verify. Highlights Knee osteoarthritis (KOA) is one of the most common orthopedic diseases. Most of the patients were elderly, and the clinical manifestations were mainly pain. This paper aims to explore the research progress of TCM acupuncture and cupping therapy for the prevention and treatment of KOA. In this paper, we reviewed the published literature, systematically evaluated and Meta analyzed the efficacy of acupuncture and cupping therapy for the treatment of knee osteoarthritis, and provided better evidence for the clinical treatment of knee osteoarthritis patients.