Interaction of rabbit C-reactive protein with phospholipid monolayers at air/water interface

摘要

C-reactive protein (CRP) is a major acute phase reactant in most mammalian species. The recognition and the binding principles of CRP to its substrates are not well known. Inthis paper the interaction of rabbit CRP (rCRP) with lipid monolayers at the air/ water interface was studied. Fromthe experiments it was concluded that rCRP molecules were amphipathic, and rCRP molecules might interact with phospholipid monolayer s by hydrophobic force. The critical surface pressure of rCRP interacting with phospholipid monolayers is about 34. 5mN/m.