Epoxide hydrolases; new tools for the synthesis of fine organic chemicals

摘要

Epoxide hydrolases are ubiquitous enzymes able to hydrolyse an epoxide to its corresponding vicinal diol. These hydrolases have been shown often to be highly enantio-and region selective, thus allowing both the epoxide and the diol to be prepared at high enantiomeric purity. Because these products show high chemical versatility, they are important for the synthesis of various biologically active products.