The morphological responses of cultured bovine aortic endothelial cells to fluid-imposed shear stress under sparse and colony conditions

摘要

The morphological responses of cultured bovine aortic endothelial cells to fluid-imposed shear stress under sparse and colony conditions were studied. Applied shear stress was controlled to 2 Pa and the exposure time was set to be between 1 and 24 hours. Before and after flow exposure, the shape index and the angle of cell orientation to flow direction of each individual cell were measured. In the experiment under sparse conditions, the shape index was 0.33±0.13 (mean±SD) and cells almost randomly distributed under the no-flow condition.