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A Second-Order Conditionally Linear Mixed Effects Model With Observed and Latent Variable Covariates

机译:具有观测和潜在变量协变量的二阶条件线性混合效应模型

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A conditionally linear mixed effects model is an appropriate framework for investigating nonlinear change in a continuous latent variable that is repeatedly measured over time. The efficacy of the model is that it allows parameters that enter the specified nonlinear time-response function to be stochastic, whereas those parameters that enter in a nonlinear manner are common to all subjects. In this article we describe how a variant of the Michaelis-Menten (M-M) function can be fit within this modeling framework using Mplus 6.0. We demonstrate how observed and latent covariates can be incorporated to help explain individual differences in growth characteristics. Features of the model including an explication of key analytic decision points are illustrated using longitudinal reading data. To aid in making this class of models accessible, annotated Mplus code is provided.
机译:有条件的线性混合效应模型是研究连续潜变量中随时间重复测量的非线性变化的合适框架。该模型的功效在于,它允许输入指定的非线性时间响应函数的参数是随机的,而以非线性方式输入的那些参数对于所有对象都是通用的。在本文中,我们描述了如何使用Mplus 6.0将Michaelis-Menten(M-M)函数的变体适合此建模框架。我们展示了如何将观察到的和潜在的协变量结合起来以帮助解释生长特征的个体差异。使用纵向读取数据来说明模型的特征,包括关键分析决策点的说明。为了帮助使此类模型易于访问,提供了带注释的Mplus代码。

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