Quinoline based sensors for bivalent copper ions in living cells

摘要

Quinoline based novel fluorescent probes have been synthesized for the selective and sensitive detection of Cu~(2+) ions. The probes FQ-1 and FQ-2 exhibit a turn-on fluorescence response towards Cu~(2+) ions under physiological conditions in living cells as well. The detection limit of Cu~(2+) using the probes FQ-1 and FQ-2 was found to be 1.8 nM and 44.2 nM respectively.