Cambridge's Randy J. Read: A Structured Approach to Biophysics

摘要

With the sequencing of the human genome now largely a done deal, researchers have turned their attention to proteomics, or the large-scale study of proteins, as the next great frontier in biology and medicine. This pursuit depends, in turn, on the very same technology—X-ray crystallography—that Crick and Watson used fifty years ago to elucidate the double-helix structure of DNA. Since then chemists and biochemists have solved the three-dimensional structure of tens of thousands of proteins, a number that will assuredly grow exponentially in the coming years.