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Health risk assessment on dietary exposure to polycyclic aromatic hydrocarbons (PAHs) in Taiyuan, China

机译:太原市膳食中暴露于多环芳烃的健康风险评估

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摘要

Twenty-five kinds of seven categories of foods were sampled in December 2008 and the concentrations of 16 polycyclic aromatic hydrocarbons (PAHs) were determined. The highest level of total PAHs was detected in pork (195.30 ng/g) whereas the lowest concentration was found in milk (8.73 ng/g). The median values of B [a]P equivalent (B[a]P_(eq)) daily exposure doses for children, adolescents, adults and seniors of male were estimated to be 392.42, 511.01, 571.56 and 532.56 ng/d, respectively, whereas those for the above population groups of female were found to be 355.16, 440.51, 487.64 and 444.85 ng/d, respectiveiy. The incremental lifetime cancer risk (ILCR) values at the 22.1th, 26.1th, 12.7th, 24.9th, 22.7th, 27.0th, 12.9th, and 25.5th percentiles for male children, male adolescents, male adults, male seniors, female children, female adolescents, female adults and female seniors, respectively, were larger than 10~(-6), indicating high potential carcinogenic risk, and were larger than 10~(-4) at the 74.5th, 78.7th, 60.6th, 77.4th, 75.3th, 79.5th, 60.8th and 77.9th percentiles for the above groups, respectively, which implied significant cancer risk. Sensitivity analysis found that the two variables of oral cancer slope factor of benzo(a) pyrene (SF) and the daily dietary PAH exposure level (ED) had the greater impact than that of body weight (BW) on the ILCR.
机译:在2008年12月,对7种食物中的25种进行了采样,并确定了16种多环芳烃(PAHs)的浓度。猪肉中总PAHs最高,为195.30 ng / g,牛奶中最低,为8.73 ng / g。男性,儿童,青少年,成人和老年人的每日B [a] P当量(B [a] P_(eq))的中位数分别估计为392.42、511.01、571.56和532.56 ng / d,而上述人群中的女性分别为355.16、440.51、487.64和444.85 ng / d。男性儿童,男性青少年,男性成年人,男性老年人,女性的22.1、26.1、12.7、24.9、22.7、27.0、12.9和25.5%百分位数的终生癌症风险(ILCR)值儿童,女性青少年,女性成年人和女性老年人分别大于10〜(-6),表明潜在的致​​癌风险,在第74.5、78.7、60.6、10,(-4)岁时,大于10〜(-4)。上述两组的百分位数分别为77.4、75.3、79.5、60.8和77.9个百分位数,这意味着有显着的癌症风险。敏感性分析发现,口腔癌斜率因子苯并(a)((SF)和每日饮食中PAH暴露水平(ED)这两个变量对ILCR的影响大于体重(BW)。

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  • 来源
    《Science of the total environment》 |2010年第22期|p.5331-5337|共7页
  • 作者单位

    Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing 100871, China;

    Department of Environmental Pollution and Health, Chinese Academy of Environmental Sciences, Beijing 100012, China;

    Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing 100871, China;

    Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing 100871, China;

    Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing 100871, China;

    Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing 100871, China;

    Taiyuan Environment Science Research and Design Institute, Taiyuan 030024, China;

    Taiyuan Environment Science Research and Design Institute, Taiyuan 030024, China;

    Taiyuan Environment Science Research and Design Institute, Taiyuan 030024, China;

    Taiyuan Environment Science Research and Design Institute, Taiyuan 030024, China;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    polycyclic aromatic hydrocarbons (PAHS); health risk assessment; dietary exposure; food; Taiyuan (China);

    机译:多环芳烃(PAHS);健康风险评估;饮食接触;餐饮;太原(中国);
  • 入库时间 2022-08-17 13:56:26

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