Fabrication of Highly Sensitive Non-Enzymatic Glucose Biosensor Based on ZnO Nanorods

摘要

In this paper, a convenient and reliable approach has been presented for the fabrication of efficient and high-sensitive non-enzymatic glucose biosensor by using well-crystalline ZnO nanorods as effective electron mediator. ZnO nanorods were synthesized by hydrothermal process at low-temperature using simply available laboratory chemicals i.e., zinc nitrate and sodium hydroxide. The detailed morphological study by field emission electron microscopy (FE-SEM) reveals that the synthesized nanorods are grown in high density. The as-synthesized nanorods are well-crystalline and possessing wurtzite hexagonal phase as confirmed by detailed structural characterizations using X-ray diffraction (XRD) and high-resolution transmission electron microscopy (HR-TEM). Fourier transform infrared (FT-IR) substantiated that the synthesized nanorods are pure ZnO. The fabricated non-enzymatic glucose biosensor based on ZnO nanorods exhibits high sensitivity of -5.601 ± 0.02 /μA cm~2 mM-1, detection limit of ~0.5 μM with a correlation coefficient (R) of 0.97531 and response time of 10 s. This research opens a way that simply synthesized ZnO nanomaterials could be used as efficient electron mediators for the fabrication of efficient non-enzymatic glucose biosensors.