Effect of ethanol on the urinary excretion of cyclohexanol and cyclohexanediols, biomarkers of the exposure to cyclohexanone, cyclohexane and cyclohexanol in humans

摘要

Objectives: This study explored the acute effect of ethanol (EtOH) on the urinary excretion of cyclohexanol (CH- ol), 1, 2-and 1, 4-cyclohexanediol (CH-diol), biomarkers of exposure to important solvents, and chemical interme- diates cyclohexanone (CH-one), cyclohexane (CH) and cyclohexanol. Conclusions: The urinary excretion of CH-diols is much less sensitive to EtOH than that of CH-ol. It is Recommended to employ CH-diols as useful and more reliable biomarkers of exposure to CH-one, CH and CH-ol in Field examinations.