The importance of the baseline Disease Activity Score 28 in determining responders and non-responders to anti-TNF in UK clinical practice

摘要

Objectives. The NICE re-appraisal of anti-TNF requires demonstration of ongoing response, making the baseline 28-joint Disease Activity Score (DAS28) crucially important. A retrospective analysis of all RA patients on their first anti-TNF determined predictive factors for those classified as non-responders at 6 months according to current NICE guidelines.