Diacerein has a weak effect on the catabolic pathway of human osteoarthritis synovial fibroblast—comparison to its effects on osteoarthritic chondrocytes

摘要

Objectives. Synoviocytes play a crucial role in the inflammatory response leading to structural damage in OA. Our aim was to assess the effects of diacerein and NSAIDs on cellular responses of synoviocytes associated with inflammation and structural integrity of cartilage in OA.