Coculture between periosteal explants and articular chondrocytes induces expression of TGF-β1 and collagen I

摘要

Objective. Repair of focal articular cartilage lesions is usually performed by employing cell-based therapeutic strategies such as autologous chondrocyte implantation (ACI). The aim of this study was to determine whether periosteum exerts pro-chondrogenic effects on the transplanted cells beyond its biomechanical role in ACI.