CCR7 (EBI1) receptor down-regulation in asthma: differential gene expression in human CD4~+ T Iymphocytes

摘要

Asthma is an inflammatory disorder, and the CD4~+ T Iymphocyte plays a key role in mediating the Inflammatory response. We used a high-density grid, Hybridization-based, differential gene expression Technology to analyse molecular mechanisms under- Lying in vivo CD4~+ T-cll activation in both steroid- Resistant asthma (SRA) and steroid-sensitive asthma (SSA).